Poster ()- #SHM19 - KEYWORDS: Atypical mycobacterium tuberculosis prostate cancer osteoarticular tuberculosis DNA probe biopsy non-necrotizing granuloma

Rare Presentation of Mycobacterium Tuberculosis Mimicking Prostate Cancer - Clinical Vignette

Seyed Mohammad Nahidi 1, BSc; Harman Singh 2, BSc; Sharang Tickoo 1, BSc; Leonidha Duka 2, MD; Jung Won 3, MD; Jennifer Gulas 3, MD
1) St. George’s University of Medicine, Grenada 2) Medical University of the Americas, Nevis 3) Wyckoff Heights Medical Center, Brooklyn, New York

ABSTRACT:
Mycobacterium tuberculosis is primarily known to affect the lungs with cavitary lesions and enlarged lymph nodes as the first telltale sign. However, if the bacteria spreads to extrapulmonary areas such as the bones, and lacks lymphadenopathy, then the differential diagnosis may become misleading. We present a case of a 68-year-old male with a chief complaint of chronic left hip pain upon which computer tomography identified lytic lesions on the left hip. Given the mildly elevated prostate-specific antigen with a family history of prostate cancer, a bone biopsy was warranted. The biopsy revealed non-caseating granulomas and the DNA probe identified the mycobacteria tuberculosis complex. This case signifies that atypical presentations of Mycobacterium tuberculosis may mimic other diagnoses and more invasive techniques such as a biopsy may be necessary.