Poster - #UMDOM7 - Clinical Vignettes (case studies)

Multinodular goiter found in patient presenting with a pituitary macroadenoma in the setting of acromegaly

Amar Arunachalam MD, Monica Lieberman-Ulm MD, Rafael Caputi MD, Silvia Gra-Menendez MD
University of Miami/Jackson Memorial Hospital

ABSTRACT
Acromegaly is a hormonal disorder as a side effect of growth hormone (GH) hypersecretion. Increased incidence of toxic multinodular goiter and thyroid carcinoma have been reported. We present a case of a patient with acromegaly who presented with a toxic multinodular goiter and hyperthyroidism. This case contributes to the theory that long-term stimulation by GH and IGF-1 of thyroid follicular cells are responsible for goiter and subsequent formation of multinodular goiter.